{"id":1572238491707,"title":"NMN Pro","handle":"prohealth-nmn-pro-125-mg-15-lozenges-ph515","description":"Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism, and gene expression in the body. When we boost NMN levels in the body, we can enhance the biosynthesis of NAD+ and alleviate symptoms associated with depletion of this crucial nutrient.\r\n\r\nIn fact, NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, insulin sensitivity, body weight, and gene expression.\r\n\r\n\u003cstrong\u003e\u003cimg style=\"float: right;padding-left: 10px;padding-bottom: 10px\" src=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/NMN-Lozenges.jpg\" alt=\"NMN Lozenges\" width=\"340\" height=\"236\"\u003eLozenges Significantly Enhance NMN Bioavailability\u003c\/strong\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eAllows the supplement to be absorbed into the blood vessels underneath the tongue\u003c\/li\u003e\r\n \t\u003cli\u003eThe NMN avoids digestion in the gastrointestinal tract and can be more rapidly delivered to the bloodstream.\u003c\/li\u003e\r\n \t\u003cli\u003eMultiple deliveries of NMN over the course of the day may dramatically enhance the therapeutic benefits of NMN*\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cstrong\u003eThe Biochemistry of NMN\u003c\/strong\u003e\r\n\r\nTo understand how NMN benefits the body, it helps to first have some background knowledge of the biochemistry of this potent compound.\r\n\r\nNicotinamide mononucleotide (NMN) is a compound derived from ribose, a sugar, and nicotinamide, also known as vitamin B3. The human body has enzymes that use NMN to generate another compound, nicotinamide adenine dinucleotide. Nicotinamide adenine dinucleotide comes in two forms: An oxidized form (NAD\u003csup\u003e+\u003c\/sup\u003e) which accepts electrons from other molecules and a reduced form (NADH) that donates electrons to other molecules.  From here on we will refer to nicotinamide adenine dinucleotide as NAD\u003csup\u003e+\u003c\/sup\u003e, but remember that it does come in these two forms.\r\n\r\n\u003cimg style=\"float: right;padding-left: 10px;padding-bottom: 10px\" src=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/NMN-image-2.gif\" alt=\"\" width=\"340\" height=\"340\"\u003e\u003cstrong\u003eNAD\u003csup\u003e+\u003c\/sup\u003e has two crucial, primary functions in the body:\u003c\/strong\u003e\r\n\u003col\u003e\r\n \t\u003cli\u003e\r\n\u003cstrong\u003eNAD\u003csup\u003e+\u003c\/sup\u003e participates in redox reactions. \u003c\/strong\u003eRedox reactions are those that involve a transfer of electrons from one reaction or molecule to another. The most well-known redox reaction in the body is cellular energy production, which includes glycolysis, the citric acid cycle, and mitochondrial respiration. NAD\u003csup\u003e+\u003c\/sup\u003e serves a vital role in each of these components of energy production.\u003c\/li\u003e\r\n \t\u003cli\u003e\r\n\u003cstrong\u003eNAD\u003csup\u003e+\u003c\/sup\u003e is a substrate for enzymes that add or remove chemical groups from proteins. \u003c\/strong\u003eFor example, NAD\u003csup\u003e+\u003c\/sup\u003e functions as a cofactor for sirtuins, proteins that regulate DNA transcription, apoptosis, inflammation, and mitochondrial biogenesis and assist in the function of poly (ADP-ribose) polymerase, a group of proteins that regulate DNA repair and genomic stability.\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\n\u003cstrong\u003eLow NAD\u003csup\u003e+\u003c\/sup\u003e Leads to Disease and Aging\u003c\/strong\u003e\r\n\r\nResearch has found that NAD\u003csup\u003e+\u003c\/sup\u003e levels decrease in aging and certain chronic disease states. The loss of NAD\u003csup\u003e+\u003c\/sup\u003e limits redox reactions and deprives enzymes of the substrate they need to function correctly; this ultimately leads to an energy deficit that impairs DNA expression and repair, promotes inflammation, and downregulates metabolism. \u003cstrong\u003eHowever, a growing body of research indicates that restoration of optimal NAD\u003csup\u003e+\u003c\/sup\u003e levels can reverse many of the symptoms associated with chronic disease and aging.\u003c\/strong\u003e How can we naturally boost the body’s levels of NAD\u003csup\u003e+\u003c\/sup\u003e? The solution lies with NMN supplementation.\r\n\r\n\u003cstrong\u003eThe Many Health Benefits of NMN \u003c\/strong\u003e\r\n\r\n\u003cstrong\u003e\u003cem\u003eEndurance and Muscle Strength\u003c\/em\u003e\u003c\/strong\u003e\r\n\r\nDecreased physical endurance and muscle strength are often considered to be “inevitable” symptoms of the normal aging process. However, recent animal research indicates that NMN can prevent these declines in aging mice. In fact, one study found that consumption of NMN enhanced endurance and muscle strength in aged mice to such a degree that they became as healthy as their much-younger peers! (\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24360282\"\u003e1\u003c\/a\u003e)(\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28068222\"\u003e2\u003c\/a\u003e)\r\n\r\n\u003cimg style=\"float: left;padding-right: 10px;padding-bottom: 10px\" src=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/NMN-image-1.gif\" alt=\"\" width=\"340\" height=\"340\"\u003e\u003cstrong\u003e\u003cem\u003eAging\u003c\/em\u003e\u003c\/strong\u003e\r\n\r\nEndurance and muscle strength are not the only physical symptoms impacted by the aging process; body weight, energy metabolism, blood lipids, insulin sensitivity, and vision are also adversely affected by the aging process. Excitingly, NMN supplementation has been found to suppress age-associated weight gain, enhance metabolism, improve insulin sensitivity and plasma lipid levels, benefit vision, and prevent adverse alterations in gene expression in aging mice. (\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28068222\"\u003e3\u003c\/a\u003e) These effects highlight the therapeutic potential of NMN as a beneficial anti-aging intervention for humans.\r\n\r\n\u003cstrong\u003e\u003cem\u003eHeart Health\u003c\/em\u003e\u003c\/strong\u003e\r\n\r\nThe human heart requires a continuous supply of ATP to fuel its muscular contractions and sustain life. \u003cstrong\u003eInterruptions in the heart’s ATP supply can impair cardiac and vascular function and contribute to the development of cardiovascular disease.\u003c\/strong\u003e By enhancing the biosynthesis of NAD\u003csup\u003e+\u003c\/sup\u003e, an essential substrate in ATP-producing reactions, NMN boosts cardiac ATP levels and significantly improves heart health. Importantly, NMN also reduces arterial aging and vascular dysfunction, two phenomena that play crucial roles in the pathogenesis of cardiovascular disease. (\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24905194\"\u003e4\u003c\/a\u003e)\r\n\r\n\u003cstrong\u003e\u003cem\u003eDNA Repair\u003c\/em\u003e\u003c\/strong\u003e\r\n\r\nYour DNA serves as the blueprint for your body’s physiological function. When DNA expression goes awry due to factors such as an unhealthy diet, environmental toxins, and aging, your body’s blueprint is intrinsically altered; this disrupts normal body function and contributes to the development of chronic health conditions such as cancer, diabetes, and neurological dysfunction. NMN helps prevent adverse changes in gene expression by repairing damaged DNA. (\u003ca href=\"http:\/\/science.sciencemag.org\/content\/355\/6331\/1312\"\u003e5\u003c\/a\u003e)\r\n\r\n\u003cstrong\u003e\u003cem\u003eWeight Management\u003c\/em\u003e\u003c\/strong\u003e\r\n\r\nWeight gain and weight loss resistance are common struggles for countless Americans. NMN is a powerful nutraceutical ally in weight loss efforts because it reverses insulin resistance, improves glucose tolerance, and ameliorates mitochondrial dysfunction, three factors that contribute to stubborn weight issues. (\u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1550413116304958\"\u003e6\u003c\/a\u003e)(\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22682224\/\"\u003e7\u003c\/a\u003e)\r\n\u003ctable align=\"center\"\u003e\r\n\u003ctbody\u003e\r\n\u003ctr\u003e\r\n\u003ctd align=\"center\"\u003eCertificate of Analysis\r\n\u003ca href=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/NMN-COA.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"\u003e\u003cimg class=\"alignleft size-full wp-image-86124\" src=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/NMN-COA_2.gif\" alt=\"NMN Certificate of Analysis\" width=\"200\" height=\"263\" border=\"0\"\u003e\u003c\/a\u003e\r\n[ \u003ca href=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/NMN-COA.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eview larger\u003c\/a\u003e ]\r\n\u003cbr\u003e\u003cbr\u003e  \r\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\r\n\u003cdiv style=\"margin: auto;text-align: center;vertical-align: middle\"\u003e\r\n\u003cimg style=\"margin-right: 10px\" src=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/logo-fda.gif\" alt=\"Manufactured in an FDA Registered Facility\" width=\"129\" height=\"92\"\u003e \u003cimg style=\"margin-left: 10px;margin-right: 10px\" src=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/logo-natural.gif\" alt=\"\" width=\"163\" height=\"134\"\u003e \u003cimg style=\"margin-left: 5px;margin-right: 10px\" src=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/logo-quality-promise.gif\" alt=\"\" width=\"134\" height=\"134\"\u003e \u003cimg style=\"padding-left: 5px\" src=\"https:\/\/www.prohealth.com\/wp-content\/uploads\/2018\/09\/logo-GMP.gif\" alt=\"\" width=\"132\" height=\"132\"\u003e\r\n\u003c\/div\u003e\r\n\u003cp style=\"clear: left\"\u003e\u003c\/p\u003e","published_at":"2018-09-14T16:52:22","created_at":"2018-09-14T16:52:22","vendor":"ProHealth","type":"Lozenges","tags":["NMN Pro"],"price":1349,"price_min":1349,"price_max":1349,"price_varies":false,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":true,"all_variant_ids":[14689184743483],"variants":[{"id":14689184743483,"product_id":1572238491707,"product_handle":"prohealth-nmn-pro-125-mg-15-lozenges-ph515","title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"PH515","requires_shipping":true,"taxable":true,"featured_image":null,"image_id":null,"available":true,"name":"NMN Pro - Default Title","options":["Default Title"],"price":1349,"weight":88,"compare_at_price":null,"inventory_quantity":1,"inventory_management":null,"inventory_policy":"deny","inventory_in_cart":0,"inventory_remaining":1,"incoming":false,"next_incoming_date":null,"taxable":true,"barcode":""}],"available":true,"images":["\/\/cdn.shopify.com\/s\/files\/1\/2426\/0449\/products\/24f13a5c791f9939e6ff2f3e7fb4ebd6_6861c870-88fc-43d4-b8a3-4a7ec231192d.jpg?v=1537036670"],"featured_image":"\/\/cdn.shopify.com\/s\/files\/1\/2426\/0449\/products\/24f13a5c791f9939e6ff2f3e7fb4ebd6_6861c870-88fc-43d4-b8a3-4a7ec231192d.jpg?v=1537036670","options":["Title"],"url":"\/products\/prohealth-nmn-pro-125-mg-15-lozenges-ph515"}

NMN Pro - 125 mg , 15 Lozenges by ProHealth

Combat Aging, Improve Heart Health and Promote Muscle Strength

  • Provides Anti-Aging Benefits by Restoring NAD+ to Youthful Levels
  • Supports Heart Health by Boosting Cardiac ATP Levels
  • Powerful Nutraceutical Ally for Healthy Weight Management
  • Serves as a precursor to NAD+
  • Lozenges significantly enhance NMN bioavailability
$13.49
Maximum quantity available reached.