ProHealth's founder, Rich Carson, set out to develop the most potent sublingual B-12 supplement on the market - and that he did! B-12 Extreme contains the world's most potent single dose of all four forms of B-12 on the market, including the only two biologically active forms in humans - methylcobalamin and dibencozide. Low blood levels of vitamin B-12 are frequently associated with fatigue and malaise. Hydroxocobalamin and methylcobalamin have also recently gained attention from leading CFS and FM researchers and doctors. MENTAL ACUITY - Methylcobalamin 12,500 mcg Methylcobalamin, perhaps the most important and potent of the essential cobalamins, plays a vital part in cell growth. Particularly important for your central nervous system, it helps promote healthy homocysteine levels and helps increase the brain's focus and clarity, and the spinal cord's function. ENERGY - Dibencozide 12,500 mcg Dibencozide- also known as Adensylcobalamin- metabolizes essential fatty acids to produce more energy. As a biologically active form of B-12, this sublingual B-12 reacts with cells to provide muscles and nerves with bursts of energy. LIVER SUPPORT - Cyanocobalamin 7,500 mcg Cyanocobalamin, the most common of the cobalamins, becomes active in your liver, creating enzymes to help the body with blood formation, cell reproduction, iron utilization, and tissue synthesis, while aiding the digestion and absorption of foods. DETOXIFICATION - Hydroxocobalamin 2,500 mcg Hydroxocobalamin, one of the three essential cobalamins that make up the vitamin B-12 complex, helps support overall detoxification. Contained in ProHealth's sublingual B12 supplement, it also assists with methylation and energy production. Dissolves under your tongue for maximum absorption. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.