Optimized Resveratrol- 250 mg , 60 vegetarian capsules by Life Extension

Positive Anti-aging Effects

  • Protects against the effects of a high-fat diet*
  • Supports youthful gene expression*
  • Supports a healthy inflammatory response*
$34.50
Usually: $34.50
$31.05

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Description

Resveratrol is a plant compound that supports the healthy expression of genes associated with slowing down aspects of the aging process — as well as overall health. Optimized Resveratrol also contains synergistic phytonutrients like quercetin, trans-pterostilbene, fisetin, plus a red grape and wild blueberry fruit blend for additional polyphenols, anthocyanins, and more.. Benefits at a Glance
  • Promotes “youthful gene expression” similar to calorie restricted diets
  • Encourages healthy insulin sensitivity and mitochondrial function
  • Supports a healthy inflammatory response
  • Contains a red grape and wild blueberry fruit extract blend
  • Augmented with synergistic trans-pterostilbene, quercetin, and fisetin
Read More About Resveratrol Studies show that calorie-restriction diets can activate youthful gene expression, a process that slows down certain aspects of aging. But resveratrol triggers many of the same favorable gene expression changes as calorie restriction, without the difficult diet to adhere to. Resveratrol’s health benefits Found in red grapes, resveratrol may be the most effective compound for maintaining optimal health and promoting longevity1 — the most active form of which is trans-resveratrol. In higher doses, resveratrol promotes healthy insulin sensitivity, encourages enhanced mitochondrial function, promotes a healthy inflammatory response, and protects against the effects of a high-fat diet.2-16 And our Optimized Resveratrol formula includes a red grape and wild blueberry blend for additional polyphenols, anthocyanins, and more. Also contains Fisetin and Quercetin The flavonol compound fisetin can "switch on" the cell-signaling molecules for youthful gene expression, DNA protection, healthy cellular function,29 and even supports vulnerable neurons against the presence of oxidative stress.28,30-34 And research indicates that fisetin synergistically enhances resveratrol, stabilizing it and shielding it from metabolic breakdown.35 Quercetin is a bioflavonoid that promotes cardiovascular health,36-39 supports healthy cholesterol levels already within normal range,40 helps reduce oxidative stress, promotes a healthy inflammatory response in blood vessel walls as a result of healthy gene expression,41 and supports healthy blood glucose levels already within normal range.42-48 References:
  1. Clin Interv Aging. 2008;3(2):331-9.
  2. Cell Metab. 2011 Nov 2;14(5):612-22.
  3. J Gerontol A Biol Sci Med Sci. 2012 Dec;67(12):1307-12.
  4. Mol Nutr Food Res. 2011 Aug;55(8):1197-206.
  5. Atherosclerosis. 2007 Apr;191(2):265-71.
  6. Mol Cancer. 2006 Oct 17;5:45.
  7. Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1246-52.
  8. Prostate. 2009 Nov 1;69(15):1668-82.
  9. Surgery. 2010 Aug;148(2):453-62.
  10. Arch Med Res. 2010 May;41(4):288-94.
  11. Dose Response. 2010 Mar 18;8(4):478-500.
  12. Food Chem Toxicol. 2011 Dec;49(12):3319-27.
  13. J Endocrinol Invest. 2011 Nov;34(10):788-92.
  14. Neurosci Lett. 2011 Oct 10;503(3):250-5.
  15. Exerc Sport Sci Rev. 2011 Jul;39(3):128-32.
  16. Nature. 2004 Aug 5;430(7000):686-9.
  17. J Pharm Pharmacol. 2006 Nov;58(11):1483-90.
  18. Clin Cancer Res. 2007 Jan 1;13(1):350-5.
  19. Phytother Res. 2008 Feb;22(2):169-79.
  20. Bioorg Med Chem. 2008 Apr 1;16(7):3800-8.
  21. BMC Med Genomics. 2008 Mar 20;1:7.
  22. J Agric Food Chem. 2008 Nov 26;56(22):10544-51.
  23. Neuro Endocrinol Lett. 2008 Oct;29(5):802-5.
  24. Life Sci. 2006 Jul 10;79(7):641-5.
  25. Lipids Health Dis. 2012 Jul 10;11:76.
  26. Neurobiol Aging. 2012 Sep;33(9):2062-71.
  27. Curr Neurovasc Res. 2009 Feb;6(1):70-81.
  28. Aging Cell. 2014 Apr;13(2):379-90.
  29. Genes Nutr. 2009 Dec;4(4):297-307]
  30. Food Chem Toxicol. 2013 Aug;58:355-61.
  31. J Med Chem. 2012 Jan 12;55(1):378-89
  32. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16568-73.
  33. Brain Res. 2007 Oct 10;1173:117-25.
  34. Hum Mol Genet. 2011 Jan 15;20(2):261-70.
  35. Xenobiotica. 2000 Sep;30(9):857-66.
  36. Mol Aspects Med. 2010 Dec;31(6):478-94.
  37. Atherosclerosis. 2011 Sep;218(1):44-52.
  38. Eur J Pharmacol. 2011 May 11;658(2-3):248-56.
  39. Eksp Klin Farmakol. 2010 Oct;73(10):14-6.
  40. Clin Chem. 2000 Aug;46(8 Pt 1):1162-70.
  41. J Thromb Haemost. 2004 Dec;2(12):2138-45.
  42. Nutr Res Pract. 2011 Feb;5(1):28-33.
  43. Biochem J. 2005;386:471-8.
  44. Int J Obes (Lond). 2011 Sep;35(9):1165-72.
  45. Biol Pharm Bull. 2008 Jul;31(7):1403-9.
  46. Rejuvenation Res. 2011 Oct;14(5):525-34.
  47. Nutrition. 2011 Jun;27(6):617-23.
  48. Am J Clin Nutr. 2010 Dec;92(6):1511-21.

Label Information

Supplement Facts
Serving Size: 1 Vegetarian Capsule
Servings Per Container: 60
Amount Per Serving %DV
Trans-Resveratrol [from Japanese knotweed (root) 250 mg **
Quercetin (as quercetin dihydrate) 150 mg **
Grape (fruit) and wild blueberry (fruit) blend  [providing polyphenols, anthocyanins, OPCs] 85 mg **
Fisetin [from wax tree extract (stem)] 10 mg **
** Daily Values not established
Do not purchase if outer seal is broken or damaged. Do not exceed recommended dose.
  • Suggested Use: Take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner.
  • Storage: Store tightly closed in a cool, dry place.
  • Contraindications: When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
  • Other Ingredients: vegetable cellulose (capsule), microcrystalline cellulose, vegetable stearate, silica, maltodextrin.

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