Goldenseal Advanced Oral Care, 4 oz by BotaniPharm

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Scientifically Formulated Goldenseal Delivers Maximum Potency for Oral Health*

  • Supports painful mouth & gum irritation
  • Maintains healthy oral tissues
  • Has a spearmint flavor for great taste & fresh breath


Goldenseal Advanced Oral Care, by Botanipharm, helps to avoid painful mouth and gum irritation by maintaining healthy oral tissues.

Goldenseal has a refreshing spearmint flavor for great taste and fresh breath. Hydrastis canadensis, or goldenseal, is a bitter herb whose beneficial effects on digestion were first shown to European Settlers by the Native Americans. Traditionally used for infections, digestive disorders, sore mouth, and wound healing, more than 3,000 scientific articles currently exist supporting the potential benefits of goldenseal and/or it primary alkaloid constituent, berberine.

Modern science has discovered these effects can be attributed to a number of compounds found in the plant called alkaloids, the primary one being berberine. Besides the active compounds in goldenseal, the plant contains other constituents which act synergistically with the alkaloids to increase their potency and/or reduce any potential adverse effects.

Another beneficial aspect of goldenseal is that it does not contribute to the emergence of drug resistant bacteria. One of the most often reported historical uses for goldenseal is for cases of bacterial induced diarrhea.

All Goldenseal products by Botanipharm are organically grown and sustainably harvested. They do not contain any wild harvested ingredients. This item cannot be shipped internationally. We sincerely apologize for any inconvenience.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Individual results may vary.

Label Information

Supplement Facts
Serving Size: 1 Teaspoon
Servings Per Container: 24
Amount Per Serving%DV
Goldenseal leaf267 mg*
Goldenseal root267 mg*
*Daily Value Not Established

Bioactivity comparable to 24 mg of Berberine. Made in the USA. Certified organic.

  • Suggested Use:

    Add 1/4 teaspoon of Goldenseal Advanced Oral Care to 1/4 cup water. Swish around the mouth for about 30 seconds then spit out or if the problem extends down into the throat, swallow.

  • Storage: Store in a cool, dry place. Keep out of reach of children.
  • Contraindications: When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating. Do not exceed recommended dose.
  • Other Ingredients: Organic spearmint essential oil, organic alcohol, and water.

Frequently Asked Questions

Answered directly by Botanipharm...

What if I am not sure if I have a Oral Thrush? Goldenseal can have a number of beneficial effects on body function particularly during times of oral imbalance. This imbalance can manifest its self in a number of ways including mouth ulcers, oral thrush, gingivitis, and more. In many instances, it can be hard to pinpoint a specific cause. One of the beautiful things about goldenseal is that it is not a drug and therefore does not just address one particular disease or set of symptoms. Goldenseal is a natural food that provides broad spectrum support for the entire digestive system regardless of the underlying cause. How does goldenseal work? First, goldenseal assists the body in maintaining healthy microbial populations in the oral cavity and the entire digestive tract. In a balanced system there are millions of beneficial microbes that perform a number of essential functions. Our laboratory studies, as well as those of others, have shown that goldenseal creates an environment that is hostile to pathogenic organisms such as Staph., Strep., E. coli, and Candida while having little to no effect on “friendly” organisms such as Lactobacillus acidophilus. In fact, our studies indicated that at eight times the concentration required to kill Staph., there was no inhibition of L. acidophilus. Secondly, goldenseal has potent anti-inflammatory properties that soothe inflamed oral linings and gums. Why should I use whole plant goldenseal instead of isolated berberine? While berberine is the primary active compound found in goldenseal, it is not the only one. There are multiple active compounds in goldenseal that work synergistically with berberine and each other to produce a balanced effect. An example, similar to conventional antibiotics, isolated berberine inhibits L. acidophilus (friendly bacteria) at the same concentration as Staph. (harmful bacteria). On the other hand, Goldenseal Advanced Digestive Support does not inhibit L. acidophilus at eight times the concentration required to inhibit Staph. even though the natural product contains almost twice as much berberine. Clearly, the whole plant product offers a protective effect to beneficial bacteria. Another example, as a part of our USDA and NIH funded research, we observed a peculiar attribute of goldenseal leaf, there was no difference between the concentration required to inhibit normal “wild” type Staph. and the concentration required to inhibit Multiple Drug Resistant (MDR) Staph. This was very interesting considering it required 32 times more ciprofloxacin to inhibit the MDR Staph than the “wild” type. Even more interesting was when ciprofloxacin was combined with goldenseal leaf extract the MDR Staph was no longer “resistant”. Our chemistry collaborators at the University of Illinois, Chicago and Ohio State University indentified a certain group of compounds in goldenseal leaf that had no antimicrobial effect when used alone but, when combined with the berberine and other active compounds in goldenseal, these newly found compounds increased the active compound’s effectiveness by as much as 5,000 times!! Using isolated berberine is similar to listening to Beethoven’s Fifth Symphony and only hearing the brass section. You get the gist of the music but you just know something is missing. How were you able to do all this research? Our leadership in the area of organic medicinal plant cultivation and processing technology has been recognized through a series of eight Small Business Innovation Research awards from USDA and the National Institutes of Health National Center for Complementary and Alternative Medicine over the past 14 years. These awards culminated in the development of goldenseal products suitable for use in NIH funded human clinical studies specifically focused on digestive tract effect. Even though we are a small family operated farm, these awards have allowed us to foster relationships with more than 30 researchers at seven major research institutions and access to analytical equipment rivaling major pharmaceutical companies. Goldenseal Advanced Support was specifically developed for use in NIH funded human clinical studies. It is, quite simply, the most thoroughly tested and documented goldenseal product on the market, produced with the attention to quality that only comes from a family run operation.